Autoimmune Brain Panel™

Consultation for Utilization of the Panel

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Microbes and Mental Illness: Past, Present, and Future

(Bransfield R., et al. Healthcare. December 29, 2023)

A wide range of microbes—including bacteria, viruses, fungi, and parasites—have been associated with conditions such as autism spectrum disorder, schizophrenia, bipolar disorder, depression, anxiety, suicidality, and behavioral dysregulation, often through mechanisms involving neuroinflammation, immune activation, and altered gene expression.

Bartonella henselae Bloodstream Infection in a Boy with Pediatric Acute-Onset Neuropsychiatric Syndrome

(Breitschwerdt E., et al. Journal of Central Nervous System Disease. March 18, 2019)

An adolescent with severe, treatment-resistant psychosis for 18 months showed progressive improvement of neuropsychiatric symptoms, was able to discontinue psychiatric medications, and returned to pre-illness activities following combination antimicrobial therapy. He also experienced a resolution of Bartonella-associated skin lesions.

Case Report: PANDAS and Persistent Lyme Disease with Neuropsychiatric Symptoms: Treatment, Resolution, and Recovery

(Cross A., et al. Frontiers in Psychiatry. February 2, 2021)

A 7-year-old girl developed relapsing neuropsychiatric symptoms after travelling to a tick-endemic area. She tested positive for Lyme disease and multiple streptococcal infections, meeting PANDAS criteria. After 31 months of antimicrobial therapy and IVIg, she achieved complete remission and remained symptom-free at the time of publication.